Cargando…
Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis
A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Dermatological Association; The Korean Society for Investigative Dermatology
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283856/ https://www.ncbi.nlm.nih.gov/pubmed/22363160 http://dx.doi.org/10.5021/ad.2012.24.1.74 |
_version_ | 1782224269099401216 |
---|---|
author | Chiba, Takahito Takahara, Masakazu Nakahara, Takeshi Fukagawa, Shuji Takei, Kenjiro Shono, Asuka Kiryu, Hiromaro Moroi, Yoichi Furue, Masutaka |
author_facet | Chiba, Takahito Takahara, Masakazu Nakahara, Takeshi Fukagawa, Shuji Takei, Kenjiro Shono, Asuka Kiryu, Hiromaro Moroi, Yoichi Furue, Masutaka |
author_sort | Chiba, Takahito |
collection | PubMed |
description | A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granulomas in the dermis. The histological diagnosis was cutaneous sarcoidosis. Systemic sarcoidosis presenting with NL has rarely been reported. The histological features of cutaneous sarcoidosis sometimes mimic those of other granulomatous diseases, including NL and granuloma annulare, which are difficult to distinguish. We discuss the novel association between sarcoidosis and other granulomatous diseases. |
format | Online Article Text |
id | pubmed-3283856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Korean Dermatological Association; The Korean Society for Investigative Dermatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-32838562012-02-23 Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis Chiba, Takahito Takahara, Masakazu Nakahara, Takeshi Fukagawa, Shuji Takei, Kenjiro Shono, Asuka Kiryu, Hiromaro Moroi, Yoichi Furue, Masutaka Ann Dermatol Case Report A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granulomas in the dermis. The histological diagnosis was cutaneous sarcoidosis. Systemic sarcoidosis presenting with NL has rarely been reported. The histological features of cutaneous sarcoidosis sometimes mimic those of other granulomatous diseases, including NL and granuloma annulare, which are difficult to distinguish. We discuss the novel association between sarcoidosis and other granulomatous diseases. Korean Dermatological Association; The Korean Society for Investigative Dermatology 2012-02 2012-02-02 /pmc/articles/PMC3283856/ /pubmed/22363160 http://dx.doi.org/10.5021/ad.2012.24.1.74 Text en Copyright © 2012 Korean Dermatological Association; The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Chiba, Takahito Takahara, Masakazu Nakahara, Takeshi Fukagawa, Shuji Takei, Kenjiro Shono, Asuka Kiryu, Hiromaro Moroi, Yoichi Furue, Masutaka Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis |
title | Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis |
title_full | Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis |
title_fullStr | Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis |
title_full_unstemmed | Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis |
title_short | Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis |
title_sort | cutaneous sarcoidosis clinically mimicking necrobiosis lipoidica in a patient with systemic sarcoidosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283856/ https://www.ncbi.nlm.nih.gov/pubmed/22363160 http://dx.doi.org/10.5021/ad.2012.24.1.74 |
work_keys_str_mv | AT chibatakahito cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT takaharamasakazu cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT nakaharatakeshi cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT fukagawashuji cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT takeikenjiro cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT shonoasuka cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT kiryuhiromaro cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT moroiyoichi cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis AT furuemasutaka cutaneoussarcoidosisclinicallymimickingnecrobiosislipoidicainapatientwithsystemicsarcoidosis |