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Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis

A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non...

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Autores principales: Chiba, Takahito, Takahara, Masakazu, Nakahara, Takeshi, Fukagawa, Shuji, Takei, Kenjiro, Shono, Asuka, Kiryu, Hiromaro, Moroi, Yoichi, Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283856/
https://www.ncbi.nlm.nih.gov/pubmed/22363160
http://dx.doi.org/10.5021/ad.2012.24.1.74
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author Chiba, Takahito
Takahara, Masakazu
Nakahara, Takeshi
Fukagawa, Shuji
Takei, Kenjiro
Shono, Asuka
Kiryu, Hiromaro
Moroi, Yoichi
Furue, Masutaka
author_facet Chiba, Takahito
Takahara, Masakazu
Nakahara, Takeshi
Fukagawa, Shuji
Takei, Kenjiro
Shono, Asuka
Kiryu, Hiromaro
Moroi, Yoichi
Furue, Masutaka
author_sort Chiba, Takahito
collection PubMed
description A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granulomas in the dermis. The histological diagnosis was cutaneous sarcoidosis. Systemic sarcoidosis presenting with NL has rarely been reported. The histological features of cutaneous sarcoidosis sometimes mimic those of other granulomatous diseases, including NL and granuloma annulare, which are difficult to distinguish. We discuss the novel association between sarcoidosis and other granulomatous diseases.
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spelling pubmed-32838562012-02-23 Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis Chiba, Takahito Takahara, Masakazu Nakahara, Takeshi Fukagawa, Shuji Takei, Kenjiro Shono, Asuka Kiryu, Hiromaro Moroi, Yoichi Furue, Masutaka Ann Dermatol Case Report A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granulomas in the dermis. The histological diagnosis was cutaneous sarcoidosis. Systemic sarcoidosis presenting with NL has rarely been reported. The histological features of cutaneous sarcoidosis sometimes mimic those of other granulomatous diseases, including NL and granuloma annulare, which are difficult to distinguish. We discuss the novel association between sarcoidosis and other granulomatous diseases. Korean Dermatological Association; The Korean Society for Investigative Dermatology 2012-02 2012-02-02 /pmc/articles/PMC3283856/ /pubmed/22363160 http://dx.doi.org/10.5021/ad.2012.24.1.74 Text en Copyright © 2012 Korean Dermatological Association; The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chiba, Takahito
Takahara, Masakazu
Nakahara, Takeshi
Fukagawa, Shuji
Takei, Kenjiro
Shono, Asuka
Kiryu, Hiromaro
Moroi, Yoichi
Furue, Masutaka
Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis
title Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis
title_full Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis
title_fullStr Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis
title_full_unstemmed Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis
title_short Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis
title_sort cutaneous sarcoidosis clinically mimicking necrobiosis lipoidica in a patient with systemic sarcoidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283856/
https://www.ncbi.nlm.nih.gov/pubmed/22363160
http://dx.doi.org/10.5021/ad.2012.24.1.74
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