Ser-634 and Ser-636 of Kaposi’s Sarcoma-Associated Herpesvirus RTA are Involved in Transactivation and are Potential Cdk9 Phosphorylation Sites

The replication and transcription activator (RTA) of Kaposi’s sarcoma-associated herpesvirus (KSHV), K-RTA, is a lytic switch protein that moderates the reactivation process of KSHV latency. By mass spectrometric analysis of affinity purified K-RTA, we showed that Thr-513 or Thr-514 was the primary...

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Detalles Bibliográficos
Autores principales: Tsai, Wan-Hua, Wang, Pei-Wen, Lin, Shu-Yu, Wu, I-Lin, Ko, Ying-Chieh, Chen, Yu-Lian, Li, Mengtao, Lin, Su-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283893/
https://www.ncbi.nlm.nih.gov/pubmed/22371709
http://dx.doi.org/10.3389/fmicb.2012.00060

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