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Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D

Macroautophagy (in this paper referred to as autophagy) and the ubiquitin–proteasome system are the two major catabolic systems in cells. Autophagy involves sequestration of cytosolic contents in double membrane–bounded vesicles called autophagosomes. The membrane source for autophagosomes has recei...

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Detalles Bibliográficos
Autores principales: Moreau, Kevin, Ravikumar, Brinda, Puri, Claudia, Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283994/
https://www.ncbi.nlm.nih.gov/pubmed/22351926
http://dx.doi.org/10.1083/jcb.201110114