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The kinetic dose limit in room-temperature time-resolved macromolecular crystallography
Protein X-ray structures are determined with ionizing radiation that damages the protein at high X-ray doses. As a result, diffraction patterns deteriorate with the increased absorbed dose. Several strategies such as sample freezing or scavenging of X-ray-generated free radicals are currently employ...
Autores principales: | Schmidt, M., Šrajer, V., Purwar, N., Tripathi, S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284346/ https://www.ncbi.nlm.nih.gov/pubmed/22338689 http://dx.doi.org/10.1107/S090904951105549X |
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