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Opposite effects of tissue inhibitor of metalloproteinases-1 (TIMP-1) over-expression and knockdown on colorectal liver metastases

BACKGROUND: Tissue inhibitors of metalloproteinases (TIMPs) and the corresponding metalloproteinases are integral parts of the protease network and have been shown to be involved in cancer development and metastasis. Paradoxically, for TIMP-1, tumor promoting as well as tumor inhibitory effects have...

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Detalles Bibliográficos
Autores principales:	Bandapalli, Obul R, Paul, Eva, Schirmacher, Peter, Brand, Karsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284431/ https://www.ncbi.nlm.nih.gov/pubmed/22230683 http://dx.doi.org/10.1186/1756-0500-5-14

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