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Induction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain

BACKGROUND: The genus Ebolavirus includes five distinct viruses. Four of these viruses cause hemorrhagic fever in humans. Currently there are no licensed vaccines for any of them; however, several vaccines are under development. Ebola virus envelope glycoprotein (GP(1,2)) is highly immunogenic, but...

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Detalles Bibliográficos
Autores principales: Ou, Wu, Delisle, Josie, Jacques, Jerome, Shih, Joanna, Price, Graeme, Kuhn, Jens H, Wang, Vivian, Verthelyi, Daniela, Kaplan, Gerardo, Wilson, Carolyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284443/
https://www.ncbi.nlm.nih.gov/pubmed/22273269
http://dx.doi.org/10.1186/1743-422X-9-32