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G Protein βγ-Subunit Signaling Mediates Airway Hyperresponsiveness and Inflammation in Allergic Asthma
Since the Gβγ subunit of Gi protein has been importantly implicated in regulating immune and inflammatory responses, this study investigated the potential role and mechanism of action of Gβγ signaling in regulating the induction of airway hyperresponsiveness (AHR) in a rabbit model of allergic asthm...
Autores principales: | Nino, Gustavo, Hu, Aihua, Grunstein, Judith S., McDonough, Joseph, Kreiger, Portia A., Josephson, Maureen B., Choi, John K., Grunstein, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284547/ https://www.ncbi.nlm.nih.gov/pubmed/22384144 http://dx.doi.org/10.1371/journal.pone.0032078 |
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