Spleen Tyrosine Kinase Regulates AP-1 Dependent Transcriptional Response to Minimally Oxidized LDL

Oxidative modification of low-density lipoprotein (LDL) turns it into an endogenous ligand recognized by pattern-recognition receptors. We have demonstrated that minimally oxidized LDL (mmLDL) binds to CD14 and mediates TLR4/MD-2-dependent responses in macrophages, many of which are MyD88-independen...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Soo-Ho, Wiesner, Philipp, Almazan, Felicidad, Kim, Jungsu, Miller, Yury I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284564/
https://www.ncbi.nlm.nih.gov/pubmed/22384232
http://dx.doi.org/10.1371/journal.pone.0032378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284564/
https://www.ncbi.nlm.nih.gov/pubmed/22384232
http://dx.doi.org/10.1371/journal.pone.0032378

Ejemplares similares