Ligand Mobility Modulates Immunological Synapse Formation and T Cell Activation

T cell receptor (TCR) engagement induces clustering and recruitment to the plasma membrane of many signaling molecules, including the protein tyrosine kinase zeta-chain associated protein of 70 kDa (ZAP70) and the adaptor SH2 domain-containing leukocyte protein of 76 kDa (SLP76). This molecular rear...

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Detalles Bibliográficos
Autores principales: Hsu, Chih-Jung, Hsieh, Wan-Ting, Waldman, Abraham, Clarke, Fiona, Huseby, Eric S., Burkhardt, Janis K., Baumgart, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284572/
https://www.ncbi.nlm.nih.gov/pubmed/22384241
http://dx.doi.org/10.1371/journal.pone.0032398

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