Cargando…

Superior Neuroprotective Efficacy of LAU-0901, a Novel Platelet-Activating Factor Antagonist, in Experimental Stroke

Platelet-activating factor (PAF) accumulates during cerebral ischemia, and inhibition of this process plays a critical role in neuronal survival. Recently, we demonstrated that LAU-0901, a novel PAF receptor antagonist, is neuroprotective in experimental stroke. We used magnetic resonance imaging in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belayev, Ludmila, Eady, Tiffany N., Khoutorova, Larissa, Atkins, Kristal D., Obenaus, Andre, Cordoba, Marta, Vaquero, Juan J., Alvarez-Builla, Julio, Bazan, Nicolas G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284672/ https://www.ncbi.nlm.nih.gov/pubmed/22408693 http://dx.doi.org/10.1007/s12975-011-0116-y

Ejemplares similares

Docosahexaenoic acid complexed to human albumin in experimental stroke: neuroprotective efficacy with a wide therapeutic window
por: Eady, Tiffany N, et al.
Publicado: (2012)

Docosahexaenoic Acid Therapy of Experimental Ischemic Stroke
por: Belayev, Ludmila, et al.
Publicado: (2010)

Docosahexaenoic Acid Signaling Modulates Cell Survival in Experimental Ischemic Stroke Penumbra and Initiates Long-Term Repair in Young and Aged Rats
por: Eady, Tiffany N., et al.
Publicado: (2012)

Synergistic Neuroprotection by a PAF Antagonist Plus a Docosanoid in Experimental Ischemic Stroke: Dose-Response and Therapeutic Window
por: Reid, Madigan M., et al.
Publicado: (2022)

Acute Treatment with Docosahexaenoic Acid Complexed to Albumin Reduces Injury after a Permanent Focal Cerebral Ischemia in Rats
por: Eady, Tiffany N., et al.
Publicado: (2013)

Integrated inflammatory signaling landscape response after delivering Elovanoid free-fatty-acid precursors leading to experimental stroke neuroprotection
por: Reid, Madigan M., et al.
Publicado: (2023)

Combined Therapy With Avastin, a PAF Receptor Antagonist and a Lipid Mediator Inhibited Glioblastoma Tumor Growth
por: Cruz Flores, Valerie A., et al.
Publicado: (2021)

Docosahexaenoic acid improves behavior and attenuates blood–brain barrier injury induced by focal cerebral ischemia in rats
por: Hong, Sung-Ha, et al.
Publicado: (2015)

Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke
por: Belayev, Ludmila, et al.
Publicado: (2017)

Blocking pro-inflammatory platelet-activating factor receptors and activating cell survival pathways: A novel therapeutic strategy in experimental ischemic stroke
por: Belayev, Ludmila, et al.
Publicado: (2020)

cRel and Wnt5a/Frizzled 5 Receptor-Mediated Inflammatory Regulation Reveal Novel Neuroprotectin D1 Targets for Neuroprotection
por: Calandria, Jorgelina M., et al.
Publicado: (2022)

Correction to: cRel and Wnt5a/Frizzled 5 Receptor-Mediated Inflammatory Regulation Reveal Novel Neuroprotectin D1 Targets for Neuroprotection
por: Calandria, Jorgelina M., et al.
Publicado: (2022)

Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2017)

NPD1 Plus RvD1 Mediated Ischemic Stroke Penumbra Protection Increases Expression of Pro-homeostatic Microglial and Astrocyte Genes
por: Reid, Madigan M., et al.
Publicado: (2023)

DHA modulates MANF and TREM2 abundance, enhances neurogenesis, reduces infarct size, and improves neurological function after experimental ischemic stroke
por: Belayev, Ludmila, et al.
Publicado: (2020)

First person – Gigi Lau and Nick Barts
Publicado: (2019)

Forest Plant and Bird Communities in the Lau Group, Fiji
por: Franklin, Janet, et al.
Publicado: (2010)

Eclairs sur l'au-delá-- Illuminations of the beyond-- = Streiflichter über das Jenseits-- /
por: Messiaen, Olivier, 1908-
Publicado: (1994)

Effects of Lactobacillus acidophilus KLDS1.0901 on Proliferation and Apoptosis of Colon Cancer Cells
por: Yue, Yingxue, et al.
Publicado: (2022)

Identifying corals displaying aberrant behavior in Fiji’s Lau Archipelago
por: Mayfield, Anderson B., et al.
Publicado: (2017)

Comparison of methods for sensitivity correction in Talbot–Lau computed tomography
por: Felsner, Lina, et al.
Publicado: (2021)

OA09.01. Massage therapy for osteoarthritis of the knee: a randomized dose-finding trial
por: Perlman, A, et al.
Publicado: (2012)

Draft Genome Sequence of the First South Korean Clinical Isolate of Burkholderia pseudomallei, H0901
por: Shin, Yong-Woo, et al.
Publicado: (2018)

IMB0901 inhibits muscle atrophy induced by cancer cachexia through MSTN signaling pathway
por: Liu, Dong, et al.
Publicado: (2019)

Science Journal - Élémentaire - No. 8: En route pour lau-dela
por: Physicists, Team
Publicado: (2022)

Excitation nucléaire dans l'atome muonique de l'Au
por: Robert Tissot, B, et al.
Publicado: (1973)

An observation on inappropriate probiotic subgroup classifications in the meta-analysis by Lau and Chamberlain
por: McFarland, Lynne V
Publicado: (2016)

Low Temperature Geomicrobiology Follows Host Rock Composition Along a Geochemical Gradient in Lau Basin
por: Sylvan, Jason B., et al.
Publicado: (2013)

Complete Genome Sequence of a Virulent Strain, Streptococcus iniae ISET0901, Isolated from Diseased Tilapia
por: Pridgeon, Julia W., et al.
Publicado: (2014)

Evaluation of a Rapid Immunochromatographic ODK-0901 Test for Detection of Pneumococcal Antigen in Middle Ear Fluids and Nasopharyngeal Secretions
por: Hotomi, Muneki, et al.
Publicado: (2012)

Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism
por: Musto, Alberto E., et al.
Publicado: (2016)

Talbot-Lau x-ray phase-contrast setup for fast scanning of large samples
por: Seifert, Maria, et al.
Publicado: (2019)

Hafnium isotope constraints on the nature of the mantle beneath the Southern Lau basin (SW Pacific)
por: Yan, Quanshu, et al.
Publicado: (2020)

Corrigendum: Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism
por: Musto, Alberto E., et al.
Publicado: (2016)

Safety and Immunogenicity of a Shigella Bivalent Conjugate Vaccine (ZF0901) in 3-Month- to 5-Year-Old Children in China
por: Mo, Yi, et al.
Publicado: (2021)

Assessing the in vivo ameliorative effects of Lactobacillus acidophilus KLDS1.0901 for induced non-alcoholic fatty liver disease treatment
por: Wang, Yanbo, et al.
Publicado: (2023)

Analysis of a silicon comb structure using an inverse Talbot–Lau neutron grating interferometer
por: Kim, Youngju, et al.
Publicado: (2022)

Bacillus safensis LAU 13: a new source of keratinase and its multi-functional biocatalytic applications
por: Lateef, Agbaje, et al.
Publicado: (2015)

Corrigenda: Hanah, a replacement name for Hana Lau, Stokvis, Ofwegen & Reimer, 2018 (preoccupied name)
por: Lau, Yee Wah, et al.
Publicado: (2020)

Symmetric Talbot-Lau neutron grating interferometry and incoherent scattering correction for quantitative dark-field imaging
por: Kim, Youngju, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6kr2r538ehr622ikd8psu6e5jh