Macrodystrophia lipomatosa involving multiple nerves

Macrodystrophia lipomatosa (MDL), a rare congenital disorder, is considered by some to be a localized form of Proteus syndrome. The implication of the PTEN (phosphatase and tensin homolog deleted on chromosome 10) gene in both strengthens this belief. We present a case who had MDL in multiple nerve...

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Autores principales: Rohilla, Seema, Jain, Nitin, Sharma, Rambaksh, Dhaulakhandi, Dhara B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284677/
https://www.ncbi.nlm.nih.gov/pubmed/21948052
http://dx.doi.org/10.1007/s10195-011-0159-6
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author Rohilla, Seema
Jain, Nitin
Sharma, Rambaksh
Dhaulakhandi, Dhara B.
author_facet Rohilla, Seema
Jain, Nitin
Sharma, Rambaksh
Dhaulakhandi, Dhara B.
author_sort Rohilla, Seema
collection PubMed
description Macrodystrophia lipomatosa (MDL), a rare congenital disorder, is considered by some to be a localized form of Proteus syndrome. The implication of the PTEN (phosphatase and tensin homolog deleted on chromosome 10) gene in both strengthens this belief. We present a case who had MDL in multiple nerve territories—all on the same side of the body—with hypertrophy of mainly fibroadipose tissue throughout their distribution, thus pointing to a form of localized hemihypertrophy; both hemihypertrophy and lipomatous tumors are components of Proteus syndrome.
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spelling pubmed-32846772012-03-08 Macrodystrophia lipomatosa involving multiple nerves Rohilla, Seema Jain, Nitin Sharma, Rambaksh Dhaulakhandi, Dhara B. J Orthop Traumatol Case Report Macrodystrophia lipomatosa (MDL), a rare congenital disorder, is considered by some to be a localized form of Proteus syndrome. The implication of the PTEN (phosphatase and tensin homolog deleted on chromosome 10) gene in both strengthens this belief. We present a case who had MDL in multiple nerve territories—all on the same side of the body—with hypertrophy of mainly fibroadipose tissue throughout their distribution, thus pointing to a form of localized hemihypertrophy; both hemihypertrophy and lipomatous tumors are components of Proteus syndrome. Springer International Publishing 2011-09-27 2012-03 /pmc/articles/PMC3284677/ /pubmed/21948052 http://dx.doi.org/10.1007/s10195-011-0159-6 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Case Report
Rohilla, Seema
Jain, Nitin
Sharma, Rambaksh
Dhaulakhandi, Dhara B.
Macrodystrophia lipomatosa involving multiple nerves
title Macrodystrophia lipomatosa involving multiple nerves
title_full Macrodystrophia lipomatosa involving multiple nerves
title_fullStr Macrodystrophia lipomatosa involving multiple nerves
title_full_unstemmed Macrodystrophia lipomatosa involving multiple nerves
title_short Macrodystrophia lipomatosa involving multiple nerves
title_sort macrodystrophia lipomatosa involving multiple nerves
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284677/
https://www.ncbi.nlm.nih.gov/pubmed/21948052
http://dx.doi.org/10.1007/s10195-011-0159-6
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AT sharmarambaksh macrodystrophialipomatosainvolvingmultiplenerves
AT dhaulakhandidharab macrodystrophialipomatosainvolvingmultiplenerves

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