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Loss of Proteostatic Control as a Substrate for Atrial Fibrillation: A Novel Target for Upstream Therapy by Heat Shock Proteins
Atrial fibrillation (AF) is the most common, sustained clinical tachyarrhythmia associated with significant morbidity and mortality. AF is a persistent condition with progressive structural remodeling of the atrial cardiomyocytes due to the AF itself, resulting in cellular changes commonly observed...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284689/ https://www.ncbi.nlm.nih.gov/pubmed/22375124 http://dx.doi.org/10.3389/fphys.2012.00036 |