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Methods for Determining the Statistical Significance of Enrichment or Depletion of Gene Ontology Classifications under Weighted Membership

High-throughput molecular biology studies, such as microarray assays of gene expression, two-hybrid experiments for detecting protein interactions, or ChIP-Seq experiments for transcription factor binding, often result in an “interesting” set of genes – say, genes that are co-expressed or bound by t...

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Detalles Bibliográficos
Autores principales: Iacucci, Ernesto, Zingg, Hans H., Perkins, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284693/
https://www.ncbi.nlm.nih.gov/pubmed/22375144
http://dx.doi.org/10.3389/fgene.2012.00024