Cargando…

Development and fine-tuning of a scale down model for process characterization studies of a monoclonal antibody upstream production process

Detalles Bibliográficos
Autores principales:	Harmsen, Mareike, Stofferis, Jimmy, Malphettes, Laetitia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Meeting Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284957/ https://www.ncbi.nlm.nih.gov/pubmed/22373535 http://dx.doi.org/10.1186/1753-6561-5-S8-P70

Ejemplares similares

Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells
por: Kochanowski, Nadine, et al.
Publicado: (2011)

Feeding strategy optimization in interaction with target seeding density of a fed-batch process for monoclonal antibody production
por: Clincke, Marie-Françoise, et al.
Publicado: (2013)

Use of Micro Bioreactor systems to streamline cell line evaluation and upstream process development for monoclonal antibody production
por: Warr, Steve R C, et al.
Publicado: (2011)

Scale-up considerations for monoclonal antibody production process: an oxygen transfer flux approach
por: Gimenez, Laura, et al.
Publicado: (2013)

Process development and optimization of fed-batch production processes for therapeutic proteins by CHO cells
por: Clincke, Marie-Françoise, et al.
Publicado: (2013)

Platform process for production of monoclonal antibodies for research purposes – improvement option
por: Petersen, Joern Meidahl, et al.
Publicado: (2011)

Evaluation of the advanced micro-scale bioreactor (ambr™) as a highthroughput tool for cell culture process development
por: Delouvroy, Frédéric, et al.
Publicado: (2013)

Process development of ATROSAB, an anti TNFR1 Monoclonal Antibody: in three steps from research to GMP
por: Landauer, Karlheinz, et al.
Publicado: (2011)

Developing an upstream process for a monoclonal antibody including medium optimization
por: Duvar, Sevim, et al.
Publicado: (2013)

From Clone Selection to 80L Bioreactor Production: Better, Faster, Leaner
por: Clincke, Marie-Françoise, et al.
Publicado: (2015)

Technology transfer and scale down model development strategy for biotherapeutics produced in mammalian cells
por: Kochanowski, Nadine, et al.
Publicado: (2013)

Challenges in scaling up a perfusion process
por: Raja, Vana, et al.
Publicado: (2011)

Characterization of binding interactions in solution between β-2-glycoprotein I and monoclonal antibodies
por: Heegaard, NHH, et al.
Publicado: (2002)

Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies
por: Yu, Xiaojie, et al.
Publicado: (2013)

Single use bioreactors for the clinical production of monoclonal antibodies – a study to analyze the performance of a CHO cell line and the quality of the produced monoclonal antibody
por: Diekmann, Sonja, et al.
Publicado: (2011)

Anti-Ige monoclonal antibody therapy for the treatment of chronic rhinosinusitis: a systematic review
por: Hong, Chris J, et al.
Publicado: (2014)

Recombinant antibody mixtures; optimization of cell line generation and single-batch manufacturing processes
por: Rasmussen, Søren K, et al.
Publicado: (2011)

Disulphide bond reduction of a therapeutic monoclonal antibody during cell culture manufacturing operations
por: Mullan, Brian, et al.
Publicado: (2011)

Preliminary evaluation of microcarrier culture for growth and monoclonal antibody production of CHO-K1 cells
por: Rodrigues, M Elisa, et al.
Publicado: (2011)

Immunodiagnosis and therapeutic immunosuppression in rheumatoid arthritis with ior t1 (anti-CD6) monoclonal antibody
por: Montero, E, et al.
Publicado: (2002)

An ultra scale‐down method to investigate monoclonal antibody processing during tangential flow filtration using ultrafiltration membranes
por: Fernandez‐Cerezo, Lara, et al.
Publicado: (2019)

Allergic diseases of the skin and drug allergies – 2017. Rapid desensitization for delayed reactions to chemotherapy and monoclonal antibodies
por: Vega Castro, Maria Aranzazu, et al.
Publicado: (2013)

Mechanics to pre-process information for the fine tuning of mechanoreceptors
por: Barth, Friedrich G.
Publicado: (2019)

Anti-Ro/SSA antibodies in systemic sclerosis (SSc): determination of the fine specificity, clinical and laboratory correlations
por: Antonioli, C, et al.
Publicado: (2002)

ambr™ Mini-bioreactor as a high-throughput tool for culture process development to accelerate transfer to stainless steel manufacturing scale: comparability study from process performance to product quality attributes
por: Delouvroy, Frédéric, et al.
Publicado: (2015)

EHMTI-0315. AMG 334, the first potent and selective human monoclonal antibody antagonist against the CGRP receptor
por: Xu, C, et al.
Publicado: (2014)

Anti-Ige monoclonal antibody therapy for the treatment of patients with chronic rhinosinusitis: a multi-disciplinary practice review
por: Kilty, Shaun J, et al.
Publicado: (2014)

Successful development of novel monoclonal antibodies against HTLV-1 bZIP factor and their applications in studying the pathogenesis of HAM/TSP
por: Saito, Mineki, et al.
Publicado: (2011)

The thyroid gland and the process of aging
por: Gesing, Adam
Publicado: (2015)

Industrial Process Scale-up
por: Harmsen, Jan
Publicado: (2013)

The FASTK family proteins fine-tune mitochondrial RNA processing
por: Ohkubo, Akira, et al.
Publicado: (2021)

Localisation of MHC Class II/HC gp-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies
por: Baeten, D, et al.
Publicado: (2003)

A new approach of endotoxic testing by using a monoclonal antibody against endotoxin (WN1-222/5) and flow cytometry
por: Staubach, K-H, et al.
Publicado: (2001)

The non-coding genome: a universe in expansion for fine-tuning the coding world
por: Luco, Reini F
Publicado: (2013)

The psychological processes involved in patient empowerment
por: Aujoulat, Isabelle, et al.
Publicado: (2012)

Fine tuning and the scale of new physics
por: Barbieri, Riccardo
Publicado: (2011)

Study of a recombinant CHO cell line producing a monoclonal antibody by ATF or TFF external filter perfusion in a WAVE Bioreactor™
por: Clincke, Marie-Françoise, et al.
Publicado: (2011)

Treatment of severe sepsis in patients with highly elevated IL-6 levels with anti-TNF monoclonal antibody MAK 195F: The Ramses study
por: Reinhart, K
Publicado: (1998)

Changes in bone density and bone turnover in patients with rheumatoid arthritis treated with rituximab, a B cell depleting monoclonal antibody (HORUS TRIAL)
por: Elshahaly, Mohsen, et al.
Publicado: (2013)

Environmental and occupational respiratory diseases – 1039. Clinical course and side effects of anti-IgE monoclonal antibody in patients with severe persistent asthma
por: Yalcin, Arzu Didem, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_2c9bia4ngmg1q6f2ugujkgdmm2