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Roles of TGFβ signaling Smads in squamous cell carcinoma

Smad proteins are classified in different groups based on their functions in mediating transforming growth factor β (TGFβ) superfamily components. Smad1/5/8 mainly mediate bone morphogenetic proteins (BMP) pathway and Smad2/3 mainly mediate TGFβ pathway. Smad4 functions as common Smad to mediate bot...

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Detalles Bibliográficos
Autores principales: Han, Gangwen, Wang, Xiao-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285038/
https://www.ncbi.nlm.nih.gov/pubmed/22204491
http://dx.doi.org/10.1186/2045-3701-1-41