Cargando…

Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

BACKGROUND: Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this may be due to chemoresistant properties of cancer stem cells (CSCs). However, our understanding of the role of CSCs in recurrent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gallagher, Michael F, Heffron, Cynthia CBB, Laios, Alexandros, O'Toole, Sharon A, Ffrench, Brendan, Smyth, Paul C, Flavin, Richard J, Elbaruni, Salah A, Spillane, Cathy D, Martin, Cara M, Sheils, Orla M, O'Leary, John J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285047/ https://www.ncbi.nlm.nih.gov/pubmed/22260314 http://dx.doi.org/10.1186/1757-2215-5-2

Ejemplares similares

An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines
por: Vencken, Sebastian F, et al.
Publicado: (2014)

Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients
por: Gallagher, Michael F, et al.
Publicado: (2009)

Suppression of Natural Killer cell NKG2D and CD226 anti-tumour cascades by platelet cloaked cancer cells: Implications for the metastatic cascade
por: Cluxton, Christopher D., et al.
Publicado: (2019)

Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer
por: McEvoy, Lynda M., et al.
Publicado: (2015)

An integrative model for recurrence in ovarian cancer
por: Laios, Alexandros, et al.
Publicado: (2008)

Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells
por: Egan, Karl, et al.
Publicado: (2011)

Aspirin and P2Y(12) inhibition attenuate platelet-induced ovarian cancer cell invasion
por: Cooke, Niamh M., et al.
Publicado: (2015)

Potential role of miR-9 and miR-223 in recurrent ovarian cancer
por: Laios, Alexandros, et al.
Publicado: (2008)

Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression
por: Aherne, Sinéad T., et al.
Publicado: (2016)

Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells
por: Li, Jinghuan, et al.
Publicado: (2007)

Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening
por: Laios, Alexandros, et al.
Publicado: (2013)

Improved RNA quality and TaqMan(® )Pre-amplification method (PreAmp) to enhance expression analysis from formalin fixed paraffin embedded (FFPE) materials
por: Li, Jinghuan, et al.
Publicado: (2008)

Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling
por: Aherne, Sinéad T, et al.
Publicado: (2008)

The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer
por: d'Adhemar, Charles J., et al.
Publicado: (2014)

Circulating tumour cell enumeration does not correlate with Miller–Payne grade in a cohort of breast cancer patients undergoing neoadjuvant chemotherapy
por: O’Toole, Sharon A., et al.
Publicado: (2020)

Comparing ion torrent with pyrosequencing and Sanger sequencing for the detection of TP53 mutations in colorectal cancer
por: Doyle, Brendan, et al.
Publicado: (2014)

MIR141 Expression Differentiates Hashimoto Thyroiditis from PTC and Benign Thyrocytes in Irish Archival Thyroid Tissues
por: Dorris, Emma R., et al.
Publicado: (2012)

Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention
por: Ffrench, Brendan, et al.
Publicado: (2014)

Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention
por: Gasch, Claudia, et al.
Publicado: (2017)

The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer
por: Bates, Mark, et al.
Publicado: (2020)

CD10(−)/ALDH(−) cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy
por: Ffrench, Brendan, et al.
Publicado: (2017)

The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon
por: Spillane, Cathy D., et al.
Publicado: (2021)

Effect of BRAF(V600E )mutation on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model
por: Cahill, Susanne, et al.
Publicado: (2007)

ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells
por: Denning, Karen, et al.
Publicado: (2008)

Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer
por: Furlong, Fiona, et al.
Publicado: (2012)

Effect of ret/PTC 1 rearrangement on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model
por: Cahill, Susanne, et al.
Publicado: (2006)

MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype
por: Lynam-Lennon, Niamh, et al.
Publicado: (2016)

CTC-5: A novel digital pathology approach to characterise circulating tumour cell biodiversity
por: Ffrench, B., et al.
Publicado: (2023)

Potentially important miRNAs in enteropathy-associated T-cell lymphoma pathogenesis: A pilot study
por: Clarke, Lindsey, et al.
Publicado: (2018)

Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness
por: Flynn, Louise, et al.
Publicado: (2020)

MicroRNA expression profiling and biomarker validation in treatment-naïve and drug resistant non-small cell lung cancer
por: MacDonagh, Lauren, et al.
Publicado: (2021)

Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines
por: Dorris, Emma R., et al.
Publicado: (2016)

Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines
por: Busschots, Steven, et al.
Publicado: (2014)

Ex vivo expansion of circulating tumour cells (CTCs)
por: Mohamed, Bashir M., et al.
Publicado: (2023)

Expression microarray analysis of papillary thyroid carcinoma and benign thyroid tissue: emphasis on the follicular variant and potential markers of malignancy
por: Finn, S. P., et al.
Publicado: (2007)

LncRNA MORT (ZNF667-AS1) in Cancer—Is There a Possible Role in Gynecological Malignancies?
por: Di Fiore, Riccardo, et al.
Publicado: (2021)

Evaluating patient attitudes to increased patient engagement with antimicrobial stewardship: a quantitative survey
por: Hughes, Gerry, et al.
Publicado: (2020)

The Lung Microbiome in COPD and Lung Cancer: Exploring the Potential of Metal-Based Drugs
por: O’Shaughnessy, Megan, et al.
Publicado: (2023)

Generic medicines and generic substitution: contrasting perspectives of stakeholders in Ireland
por: O’Leary, A., et al.
Publicado: (2015)

Integrating biomarkers across omic platforms: an approach to improve stratification of patients with indolent and aggressive prostate cancer
por: Murphy, Keefe, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9bnt1oddgu3kbt6ssmoqefonvo