L type Ca(2+ )channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats

BACKGROUND: Oxaliplatin is an important drug used in the treatment of colorectal cancer. However, it frequently causes severe acute and chronic peripheral neuropathies. We recently reported that repeated administration of oxaliplatin induced cold hyperalgesia in the early phase and mechanical allody...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawashiri, Takehiro, Egashira, Nobuaki, Kurobe, Kentaro, Tsutsumi, Kuniaki, Yamashita, Yuji, Ushio, Soichiro, Yano, Takahisa, Oishi, Ryozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285049/
https://www.ncbi.nlm.nih.gov/pubmed/22292988
http://dx.doi.org/10.1186/1744-8069-8-7

Ejemplares similares

Ejemplares similares