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A 24-Hour Temporal Profile of In Vivo Brain and Heart PET Imaging Reveals a Nocturnal Peak in Brain (18)F-Fluorodeoxyglucose Uptake
Using positron emission tomography, we measured in vivo uptake of (18)F-fluorodeoxyglucose (FDG) in the brain and heart of C57Bl/6 mice at intervals across a 24-hour light-dark cycle. Our data describe a significant, high amplitude rhythm in FDG uptake throughout the whole brain, peaking at the mid-...
Autores principales: | van der Veen, Daan R., Shao, Jinping, Chapman, Sarah, Leevy, W. Matthew, Duffield, Giles E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285174/ https://www.ncbi.nlm.nih.gov/pubmed/22384076 http://dx.doi.org/10.1371/journal.pone.0031792 |
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