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A 24-Hour Temporal Profile of In Vivo Brain and Heart PET Imaging Reveals a Nocturnal Peak in Brain (18)F-Fluorodeoxyglucose Uptake

Using positron emission tomography, we measured in vivo uptake of (18)F-fluorodeoxyglucose (FDG) in the brain and heart of C57Bl/6 mice at intervals across a 24-hour light-dark cycle. Our data describe a significant, high amplitude rhythm in FDG uptake throughout the whole brain, peaking at the mid-...

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Detalles Bibliográficos
Autores principales: van der Veen, Daan R., Shao, Jinping, Chapman, Sarah, Leevy, W. Matthew, Duffield, Giles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285174/
https://www.ncbi.nlm.nih.gov/pubmed/22384076
http://dx.doi.org/10.1371/journal.pone.0031792

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