Phenotypic Detection of Clonotypic B Cells in Multiple Myeloma by Specific Immunoglobulin Ligands Reveals their Rarity in Multiple Myeloma

In multiple myeloma, circulating “clonotypic” B cells, that express the immunoglobulin rearrangement of the malignant plasma cell clone, can be indirectly detected by PCR. Their role as potential “feeder” cells for the malignant plasma cell pool remains controversial. Here we established for the fir...

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Detalles Bibliográficos
Autores principales: Trepel, Martin, Martens, Victoria, Doll, Christian, Rahlff, Janina, Gösch, Barbara, Loges, Sonja, Binder, Mascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285203/
https://www.ncbi.nlm.nih.gov/pubmed/22384124
http://dx.doi.org/10.1371/journal.pone.0031998

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