Biochemical Analysis of Matrix Metalloproteinase Activation of Chemokines CCL15 and CCL23 and Increased Glycosaminoglycan Binding of CCL16

Leukocyte migration and activation is orchestrated by chemokines, the cleavage of which modulates their activity and glycosaminoglycan binding and thus their roles in inflammation and immunity. Early research identified proteolysis as a means of both activating or inactivating CXC chemokines and ina...

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Detalles Bibliográficos
Autores principales: Starr, Amanda E., Dufour, Antoine, Maier, Josefine, Overall, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285354/
https://www.ncbi.nlm.nih.gov/pubmed/22147696
http://dx.doi.org/10.1074/jbc.M111.314609

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