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Complete subunit architecture of the proteasome regulatory particle

The proteasome is the major ATP-dependent protease in eukaryotic cells, but limited structural information strongly restricts a mechanistic understanding of its activities. The proteasome regulatory particle, consisting of the lid and base subcomplexes, recognizes and processes poly-ubiquitinated su...

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Detalles Bibliográficos
Autores principales: Lander, Gabriel C., Estrin, Eric, Matyskiela, Mary E., Bashore, Charlene, Nogales, Eva, Martin, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285539/
https://www.ncbi.nlm.nih.gov/pubmed/22237024
http://dx.doi.org/10.1038/nature10774