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Sprouty4 Is an Endogenous Negative Modulator of TrkA Signaling and Neuronal Differentiation Induced by NGF

The Sprouty (Spry) family of proteins represents endogenous regulators of downstream signaling pathways induced by receptor tyrosine kinases (RTKs). Using real time PCR, we detect a significant increase in the expression of Spry4 mRNA in response to NGF, indicating that Spry4 could modulate intracel...

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Detalles Bibliográficos
Autores principales:	Alsina, Fernando C., Irala, Dolores, Fontanet, Paula A., Hita, Francisco J., Ledda, Fernanda, Paratcha, Gustavo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285629/ https://www.ncbi.nlm.nih.gov/pubmed/22384148 http://dx.doi.org/10.1371/journal.pone.0032087

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