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Biophysical Characterization and Membrane Interaction of the Two Fusion Loops of Glycoprotein B from Herpes Simplex Type I Virus

The molecular mechanism of entry of herpesviruses requires a multicomponent fusion system. Cell invasion by Herpes simplex virus (HSV) requires four virally encoded glycoproteins: namely gD, gB and gH/gL. The role of gB has remained elusive until recently when the crystal structure of HSV-1 gB becam...

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Detalles Bibliográficos
Autores principales: Falanga, Annarita, Tarallo, Rossella, Vitiello, Giuseppe, Vitiello, Mariateresa, Perillo, Emiliana, Cantisani, Marco, D'Errico, Gerardino, Galdiero, Massimiliano, Galdiero, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285657/
https://www.ncbi.nlm.nih.gov/pubmed/22384173
http://dx.doi.org/10.1371/journal.pone.0032186