IKAP/Elp1 Is Required In Vivo for Neurogenesis and Neuronal Survival, but Not for Neural Crest Migration

Familial Dysautonomia (FD; Hereditary Sensory Autonomic Neuropathy; HSAN III) manifests from a failure in development of the peripheral sensory and autonomic nervous systems. The disease results from a point mutation in the IKBKAP gene, which encodes the IKAP protein, whose function is still unresol...

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Detalles Bibliográficos
Autores principales: Hunnicutt, Barbara J., Chaverra, Marta, George, Lynn, Lefcort, Frances
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285659/
https://www.ncbi.nlm.nih.gov/pubmed/22384137
http://dx.doi.org/10.1371/journal.pone.0032050

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