Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20

Toll-like receptor (TLR) signaling is linked to autophagy that facilitates elimination of intracellular pathogens. However, it is largely unknown whether autophagy controls TLR signaling. Here, we report that poly(I:C) stimulation induces selective autophagic degradation of the TLR adaptor molecule...

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Detalles Bibliográficos
Autores principales: Inomata, Megumi, Niida, Shumpei, Shibata, Ken-ichiro, Into, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285758/
https://www.ncbi.nlm.nih.gov/pubmed/21964925
http://dx.doi.org/10.1007/s00018-011-0819-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285758/
https://www.ncbi.nlm.nih.gov/pubmed/21964925
http://dx.doi.org/10.1007/s00018-011-0819-y

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