Cargando…
Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20
Toll-like receptor (TLR) signaling is linked to autophagy that facilitates elimination of intracellular pathogens. However, it is largely unknown whether autophagy controls TLR signaling. Here, we report that poly(I:C) stimulation induces selective autophagic degradation of the TLR adaptor molecule...
Autores principales: | Inomata, Megumi, Niida, Shumpei, Shibata, Ken-ichiro, Into, Takeshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285758/ https://www.ncbi.nlm.nih.gov/pubmed/21964925 http://dx.doi.org/10.1007/s00018-011-0819-y |
Ejemplares similares
-
The Role of Autophagy and Autophagy Receptor NDP52 in Microbial Infections
por: Fan, Shuangqi, et al.
Publicado: (2020) -
Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy
por: Vargas, Jose Norberto S., et al.
Publicado: (2019) -
Streptococcus pneumoniae triggers hierarchical autophagy through reprogramming of LAPosome-like vesicles via NDP52-delocalization
por: Ogawa, Michinaga, et al.
Publicado: (2020) -
The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria
por: Ravenhill, Benjamin J., et al.
Publicado: (2019) -
Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
por: Into, Takeshi, et al.
Publicado: (2017)