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NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

Multiple sclerosis is a chronic inflammatory disease of the central nervous system, associated with demyelination and neurodegeneration. The mechanisms of tissue injury are poorly understood, but recent data suggest that mitochondrial injury may play an important role in this process. Mitochondrial...

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Detalles Bibliográficos
Autores principales: Fischer, Marie T., Sharma, Rakhi, Lim, Jamie L., Haider, Lukas, Frischer, Josa M., Drexhage, Joost, Mahad, Don, Bradl, Monika, van Horssen, Jack, Lassmann, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286337/
https://www.ncbi.nlm.nih.gov/pubmed/22366799
http://dx.doi.org/10.1093/brain/aws012