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A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin

Drosophila melanogaster crammer is a novel cathepsin inhibitor that is involved in LTM (long-term memory) formation. The mechanism by which the inhibitory activity is regulated remains unclear. In the present paper we have shown that the oligomeric state of crammer is pH dependent. At neutral pH, cr...

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Detalles Bibliográficos
Autores principales:	Tseng, Tien-Sheng, Cheng, Chao-Sheng, Chen, Dian-Jiun, Shih, Min-Fang, Liu, Yu-Nan, Hsu, Shang-Te Danny, Lyu, Ping-Chiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286859/ https://www.ncbi.nlm.nih.gov/pubmed/22150223 http://dx.doi.org/10.1042/BJ20111360

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