New Insights into the Immunological Changes in IL-10-Deficient Mice during the Course of Spontaneous Inflammation in the Gut Mucosa

IL-10 is a regulatory cytokine that plays a major role in the homeostasis of the gut and this is illustrated by the fact that IL-10(−/−) mice develop spontaneous colitis. In this study, IL-10(−/−) mice were analyzed for immunological changes during colitis development. We found a reduced frequency o...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomes-Santos, Ana Cristina, Moreira, Thais Garcias, Castro-Junior, Archimedes Barbosa, Horta, Bernardo Coelho, Lemos, Luisa, Cruz, Deborah Nogueira, Guimarães, Mauro Andrade Freitas, Cara, Denise Carmona, McCafferty, Donna-Marie, Faria, Ana Maria Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287045/
https://www.ncbi.nlm.nih.gov/pubmed/22400037
http://dx.doi.org/10.1155/2012/560817

Ejemplares similares

Ejemplares similares