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RNA self-cleavage activated by ultraviolet light-induced oxidation

A novel UV-C-light-induced ribozyme activity was discovered within the highly structured 5′-genomic regions of both Hepatitis C Virus (HCV) and the related Classic Swine Fever Virus (CSFV). Cleavage is mediated by exposure to UV-C light but not by exogenous oxygen radicals. It is also very selective...

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Detalles Bibliográficos
Autores principales:	Ariza-Mateos, Ascensión, Prieto-Vega, Samuel, Díaz-Toledano, Rosa, Birk, Alex, Szeto, Hazel, Mena, Ignacio, Berzal-Herranz, Alfredo, Gómez, Jordi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287179/ https://www.ncbi.nlm.nih.gov/pubmed/21989404 http://dx.doi.org/10.1093/nar/gkr822

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