Cargando…

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA

We have previously reported that DT40 cells deficient in the Y-family polymerase REV1 are defective in replicating G-quadruplex DNA. In vivo this leads to uncoupling of DNA synthesis from redeposition of histones displaced ahead of the replication fork, which in turn leads to loss of transcriptional...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarkies, Peter, Murat, Pierre, Phillips, Lara G., Patel, K.J., Balasubramanian, Shankar, Sale, Julian E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287192/ https://www.ncbi.nlm.nih.gov/pubmed/22021381 http://dx.doi.org/10.1093/nar/gkr868

Ejemplares similares

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression
por: Fernando, Himesh, et al.
Publicado: (2009)

Epigenetic regulation by RARα maintains ligand-independent transcriptional activity
por: Laursen, Kristian B., et al.
Publicado: (2012)

Guanine quadruplex structures localize to heterochromatin
por: Hoffmann, Roland F., et al.
Publicado: (2016)

Detection of G-quadruplex DNA in mammalian cells
por: Henderson, Alexander, et al.
Publicado: (2014)

The Drosophila MLR COMPASS complex is essential for programming cis-regulatory information and maintaining epigenetic memory during development
por: Zraly, Claudia B, et al.
Publicado: (2020)

CNBP controls transcription by unfolding DNA G-quadruplex structures
por: David, Aldana P, et al.
Publicado: (2019)

G-quadruplex ligands mediate downregulation of DUX4 expression
por: Ciszewski, Lukasz, et al.
Publicado: (2020)

Vimentin binds to G-quadruplex repeats found at telomeres and gene promoters
por: Ceschi, Silvia, et al.
Publicado: (2022)

TERRA regulates DNA G-quadruplex formation and ATRX recruitment to chromatin
por: Tsai, Ru-Xuan, et al.
Publicado: (2022)

ZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells
por: Anvar, Zahra, et al.
Publicado: (2016)

Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma
por: Xu, Ying-Zhi, et al.
Publicado: (2020)

Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability
por: Nizialek, Emily A., et al.
Publicado: (2016)

G-quadruplexes as novel cis-elements controlling transcription during embryonic development
por: David, Aldana P., et al.
Publicado: (2016)

Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes
por: Roach, Ruby J, et al.
Publicado: (2020)

Identification of LARK as a novel and conserved G-quadruplex binding protein in invertebrates and vertebrates
por: Niu, Kangkang, et al.
Publicado: (2019)

Novel roles of an intragenic G-quadruplex in controlling microRNA expression and cardiac function
por: Zhu, Min, et al.
Publicado: (2021)

Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase
por: El-Khoury, Roberto, et al.
Publicado: (2023)

DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells
por: Veland, Nicolas, et al.
Publicado: (2019)

Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance
por: Zizza, Pasquale, et al.
Publicado: (2016)

G-quadruplex DNA contributes to RNA polymerase II-mediated 3D chromatin architecture
por: Yuan, Jun, et al.
Publicado: (2023)

Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation
por: Jeffery, Daniel C. B., et al.
Publicado: (2013)

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
por: Johnson, Jay E., et al.
Publicado: (2010)

Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene
por: Sun, Daekyu, et al.
Publicado: (2011)

Location dependence of the transcriptional response of a potential G-quadruplex in gene promoters under oxidative stress
por: Fleming, Aaron M, et al.
Publicado: (2019)

The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma
por: Lago, Sara, et al.
Publicado: (2021)

A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro
por: Raiber, Eun-Ang, et al.
Publicado: (2012)

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property
por: Cogoi, Susanna, et al.
Publicado: (2014)

Double-stranded flanking ends affect the folding kinetics and conformational equilibrium of G-quadruplexes forming sequences within the promoter of KIT oncogene
por: Vesco, Guglielmo, et al.
Publicado: (2021)

Epigenetic features of human telomeres
por: Cubiles, María D, et al.
Publicado: (2018)

Yin Yang 1 contains G-quadruplex structures in its promoter and 5′-UTR and its expression is modulated by G4 resolvase 1
por: Huang, Weiwei, et al.
Publicado: (2012)

A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress
por: Wei, Pei-Chi, et al.
Publicado: (2013)

Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo
por: Hirashima, Kyotaro, et al.
Publicado: (2015)

Loci specific epigenetic drug sensitivity
por: Zhang, Thanutra, et al.
Publicado: (2020)

The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells
por: Pramanik, Suravi, et al.
Publicado: (2022)

Epigenetic diversity of Kaposi’s sarcoma–associated herpesvirus
por: Darst, Russell P., et al.
Publicado: (2013)

Epigenetic instability of imprinted genes in human cancers
por: Kim, Joomyeong, et al.
Publicado: (2015)

Epigenetic plasticity safeguards heterochromatin configuration in mammals
por: Fukuda, Kei, et al.
Publicado: (2023)

The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes
por: Thön, Marcel, et al.
Publicado: (2010)

Mechanisms coordinating ribosomal protein gene transcription in response to stress
por: Zencir, Sevil, et al.
Publicado: (2020)

Myod1 and GR coordinate myofiber-specific transcriptional enhancers
por: Rovito, Daniela, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ndua9da34qdqav6v0aldr6e8bv