DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

Synthetic scaffolds that permit spatial and temporal organization of enzymes in living cells are a promising post-translational strategy for controlling the flow of information in both metabolic and signaling pathways. Here, we describe the use of plasmid DNA as a stable, robust and configurable sca...

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Detalles Bibliográficos
Autores principales: Conrado, Robert J., Wu, Gabriel C., Boock, Jason T., Xu, Hansen, Chen, Susan Y., Lebar, Tina, Turnšek, Jernej, Tomšič, Nejc, Avbelj, Monika, Gaber, Rok, Koprivnjak, Tomaž, Mori, Jerneja, Glavnik, Vesna, Vovk, Irena, Benčina, Mojca, Hodnik, Vesna, Anderluh, Gregor, Dueber, John E., Jerala, Roman, DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287197/
https://www.ncbi.nlm.nih.gov/pubmed/22021385
http://dx.doi.org/10.1093/nar/gkr888

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