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Direct evidence of nuclear Argonaute distribution during transcriptional silencing links the actin cytoskeleton to nuclear RNAi machinery in human cells

Mammalian RNAi machinery facilitating transcriptional gene silencing (TGS) is the RNA-induced transcriptional gene silencing-like (RITS-like) complex, comprising of Argonaute (Ago) and small interfering RNA (siRNA) components. We have previously demonstrated promoter-targeted siRNA induce TGS in hum...

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Detalles Bibliográficos
Autores principales:	Ahlenstiel, Chantelle L., Lim, Heidi G. W., Cooper, David A., Ishida, Takaomi, Kelleher, Anthony D., Suzuki, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287199/ https://www.ncbi.nlm.nih.gov/pubmed/22064859 http://dx.doi.org/10.1093/nar/gkr891

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