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Interferon gamma (IFN-γ) disrupts energy expenditure and metabolic homeostasis by suppressing SIRT1 transcription

Chronic inflammation impairs metabolic homeostasis and is intimately correlated with the pathogenesis of type 2 diabetes. The pro-inflammatory cytokine IFN-γ is an integral part of the metabolic inflammation circuit and contributes significantly to metabolic dysfunction. The underlying mechanism, ho...

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Detalles Bibliográficos
Autores principales:	Li, Ping, Zhao, Yuhao, Wu, Xiaoyan, Xia, Minjie, Fang, Mingming, Iwasaki, Yasumasa, Sha, Jiahao, Chen, Qi, Xu, Yong, Shen, Aiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287208/ https://www.ncbi.nlm.nih.gov/pubmed/22064865 http://dx.doi.org/10.1093/nar/gkr984

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