Dorsal root ganglion – a potential new therapeutic target for neuropathic pain

A regional approach can protect our patients from often unacceptable adverse effects produced by systematically applied drugs. Regional therapeutic approaches, as well as interventions at the level of the peripheral nervous system and particularly the dorsal root ganglion (DRG), represent an alterna...

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Detalles Bibliográficos
Autores principales: Sapunar, Damir, Kostic, Sandra, Banozic, Adriana, Puljak, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287412/
https://www.ncbi.nlm.nih.gov/pubmed/22375099
http://dx.doi.org/10.2147/JPR.S26603
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author Sapunar, Damir
Kostic, Sandra
Banozic, Adriana
Puljak, Livia
author_facet Sapunar, Damir
Kostic, Sandra
Banozic, Adriana
Puljak, Livia
author_sort Sapunar, Damir
collection PubMed
description A regional approach can protect our patients from often unacceptable adverse effects produced by systematically applied drugs. Regional therapeutic approaches, as well as interventions at the level of the peripheral nervous system and particularly the dorsal root ganglion (DRG), represent an alternative to the systemic application of therapeutic agents. This article provides an overview of DRG anatomical peculiarities, explains why the DRG is an important therapeutic target, and how animal models of targeted drug delivery can help us in the translation of basic research into clinical practice.
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spelling pubmed-32874122012-02-28 Dorsal root ganglion – a potential new therapeutic target for neuropathic pain Sapunar, Damir Kostic, Sandra Banozic, Adriana Puljak, Livia J Pain Res Perspectives A regional approach can protect our patients from often unacceptable adverse effects produced by systematically applied drugs. Regional therapeutic approaches, as well as interventions at the level of the peripheral nervous system and particularly the dorsal root ganglion (DRG), represent an alternative to the systemic application of therapeutic agents. This article provides an overview of DRG anatomical peculiarities, explains why the DRG is an important therapeutic target, and how animal models of targeted drug delivery can help us in the translation of basic research into clinical practice. Dove Medical Press 2012-02-16 /pmc/articles/PMC3287412/ /pubmed/22375099 http://dx.doi.org/10.2147/JPR.S26603 Text en © 2012 Sapunar et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Perspectives
Sapunar, Damir
Kostic, Sandra
Banozic, Adriana
Puljak, Livia
Dorsal root ganglion – a potential new therapeutic target for neuropathic pain
title Dorsal root ganglion – a potential new therapeutic target for neuropathic pain
title_full Dorsal root ganglion – a potential new therapeutic target for neuropathic pain
title_fullStr Dorsal root ganglion – a potential new therapeutic target for neuropathic pain
title_full_unstemmed Dorsal root ganglion – a potential new therapeutic target for neuropathic pain
title_short Dorsal root ganglion – a potential new therapeutic target for neuropathic pain
title_sort dorsal root ganglion – a potential new therapeutic target for neuropathic pain
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287412/
https://www.ncbi.nlm.nih.gov/pubmed/22375099
http://dx.doi.org/10.2147/JPR.S26603
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AT puljaklivia dorsalrootganglionapotentialnewtherapeutictargetforneuropathicpain

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