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Drug-drug relationship based on target information: application to drug target identification

BACKGROUND: Drugs that bind to common targets likely exert similar activities. In this target-centric view, the inclusion of richer target information may better represent the relationships between drugs and their activities. Under this assumption, we expanded the “common binding rule” assumption of...

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Detalles Bibliográficos
Autores principales: Park, Keunwan, Kim, Dongsup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287478/
https://www.ncbi.nlm.nih.gov/pubmed/22784569
http://dx.doi.org/10.1186/1752-0509-5-S2-S12