Cargando…

Novel Markov model of induced pluripotency predicts gene expression changes in reprogramming

BACKGROUND: Somatic cells can be reprogrammed to induced-pluripotent stem cells (iPSCs) by introducing few reprogramming factors, which challenges the long held view that cell differentiation is irreversible. However, the mechanism of induced pluripotency is still unknown. METHODS: Inspired by the p...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Zhirui, Qian, Minping, Zhang, Michael Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287488/
https://www.ncbi.nlm.nih.gov/pubmed/22784579
http://dx.doi.org/10.1186/1752-0509-5-S2-S8