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Novel Markov model of induced pluripotency predicts gene expression changes in reprogramming

BACKGROUND: Somatic cells can be reprogrammed to induced-pluripotent stem cells (iPSCs) by introducing few reprogramming factors, which challenges the long held view that cell differentiation is irreversible. However, the mechanism of induced pluripotency is still unknown. METHODS: Inspired by the p...

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Detalles Bibliográficos
Autores principales:	Hu, Zhirui, Qian, Minping, Zhang, Michael Q
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287488/ https://www.ncbi.nlm.nih.gov/pubmed/22784579 http://dx.doi.org/10.1186/1752-0509-5-S2-S8

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