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Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome
BACKGROUND: DNA methylation in the 5' promoter regions of genes and microRNA (miRNA) regulation at the 3' untranslated regions (UTRs) are two major epigenetic regulation mechanisms in most eukaryotes. Both DNA methylation and miRNA regulation can suppress gene expression and their correspo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287497/ https://www.ncbi.nlm.nih.gov/pubmed/22369656 http://dx.doi.org/10.1186/1471-2164-12-S5-S15 |