Cargando…
Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits?
The common disease/rare variant hypothesis predicts that rare variants with large effects will have a strong impact on corresponding phenotypes. Therefore it is assumed that rare functional variants are enriched in the extremes of the phenotype distribution. In this analysis of the Genetic Analysis...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287828/ https://www.ncbi.nlm.nih.gov/pubmed/22373517 http://dx.doi.org/10.1186/1753-6561-5-S9-S105 |