Detection of rare variant effects in association studies: extreme values, iterative regression, and a hybrid approach

We develop statistical methods for detecting rare variants that are associated with quantitative traits. We propose two strategies and their combination for this purpose: the iterative regression strategy and the extreme values strategy. In the iterative regression strategy, we use iterative regress...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaogong, Sha, Qiuying, Wang, Xinli, Zhang, Shuanglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287836/
https://www.ncbi.nlm.nih.gov/pubmed/22373188
http://dx.doi.org/10.1186/1753-6561-5-S9-S112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287836/
https://www.ncbi.nlm.nih.gov/pubmed/22373188
http://dx.doi.org/10.1186/1753-6561-5-S9-S112

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