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Gene-based partial least-squares approaches for detecting rare variant associations with complex traits
Genome-wide association studies are largely based on single-nucleotide polymorphisms and rest on the common disease/common variants (single-nucleotide polymorphisms) hypothesis. However, it has been argued in the last few years and is well accepted now that rare variants are valuable for studying co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287853/ https://www.ncbi.nlm.nih.gov/pubmed/22373126 http://dx.doi.org/10.1186/1753-6561-5-S9-S19 |