Cargando…
Incorporating predicted functions of nonsynonymous variants into gene-based analysis of exome sequencing data: a comparative study
Next-generation sequencing has opened up new avenues for the genetic study of complex traits. However, because of the small number of observations for any given rare allele and high sequencing error, it is a challenge to identify functional rare variants associated with the phenotype of interest. Re...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287855/ https://www.ncbi.nlm.nih.gov/pubmed/22373178 http://dx.doi.org/10.1186/1753-6561-5-S9-S20 |