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Identifying causal rare variants of disease through family-based analysis of Genetics Analysis Workshop 17 data set

Linkage- and association-based methods have been proposed for mapping disease-causing rare variants. Based on the family information provided in the Genetic Analysis Workshop 17 data set, we formulate a two-pronged approach that combines both methods. Using the identity-by-descent information provid...

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Detalles Bibliográficos
Autores principales:	Yip, Wai-Ki, De, Gourab, Raby, Benjamin A, Laird, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287856/ https://www.ncbi.nlm.nih.gov/pubmed/22373204 http://dx.doi.org/10.1186/1753-6561-5-S9-S21

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