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Pathway analysis for family data using nested random-effects models
Recently we proposed a novel two-step approach to test for pathway effects in disease progression. The goal of this approach is to study the joint effect of multiple single-nucleotide polymorphisms that belong to certain genes. By using random effects, our approach acknowledges the correlations with...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287857/ https://www.ncbi.nlm.nih.gov/pubmed/22373228 http://dx.doi.org/10.1186/1753-6561-5-S9-S22 |