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Exploration and comparison of methods for combining population- and family-based genetic association using the Genetic Analysis Workshop 17 mini-exome

We examine the performance of various methods for combining family- and population-based genetic association data. Several approaches have been proposed for situations in which information is collected from both a subset of unrelated subjects and a subset of family members. Analyzing these samples s...

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Detalles Bibliográficos
Autores principales: Fardo, David W, Druen, Anthony R, Liu, Jinze, Mirea, Lucia, Infante-Rivard, Claire, Breheny, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287863/
https://www.ncbi.nlm.nih.gov/pubmed/22373349
http://dx.doi.org/10.1186/1753-6561-5-S9-S28