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Challenges and directions: an analysis of Genetic Analysis Workshop 17 data by collapsing rare variants within family data

Recent studies suggest that the traditional case-control study design does not have sufficient power to discover rare risk variants. Two different methods—collapsing and family data—are suggested as alternatives for discovering these rare variants. Compared with common variants, rare variants have u...

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Detalles Bibliográficos
Autores principales:	Lin, Peng, Hamm, Michael, Hartz, Sarah, Zhang, Zhehao, Rice, John P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287866/ https://www.ncbi.nlm.nih.gov/pubmed/22373451 http://dx.doi.org/10.1186/1753-6561-5-S9-S30

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