Cargando…
Evaluating methods for combining rare variant data in pathway-based tests of genetic association
Analyzing sets of genes in genome-wide association studies is a relatively new approach that aims to capitalize on biological knowledge about the interactions of genes in biological pathways. This approach, called pathway analysis or gene set analysis, has not yet been applied to the analysis of rar...
Autores principales: | Petersen, Ashley, Sitarik, Alexandra, Luedtke, Alexander, Powers, Scott, Bekmetjev, Airat, Tintle, Nathan L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287885/ https://www.ncbi.nlm.nih.gov/pubmed/22373429 http://dx.doi.org/10.1186/1753-6561-5-S9-S48 |
Ejemplares similares
-
Evaluating methods for the analysis of rare variants in sequence data
por: Luedtke, Alexander, et al.
Publicado: (2011) -
Comparing gene set analysis methods on single-nucleotide polymorphism data from Genetic Analysis Workshop 16
por: Tintle, Nathan L, et al.
Publicado: (2009) -
Application of family-based tests of association for rare variants to pathways
por: Greco, Brian, et al.
Publicado: (2014) -
Evaluation of the power and type I error of recently proposed family-based tests of association for rare variants
por: Hainline, Allison, et al.
Publicado: (2014) -
A general method for combining different family-based rare-variant tests of association to improve power and robustness of a wide range of genetic architectures
por: Green, Alden, et al.
Publicado: (2016)