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Identification of functional rare variants in genome-wide association studies using stability selection based on random collapsing
Genome-wide association studies are a powerful approach used to identify common variants for complex disease. However, the traditional genome-wide association methods may not be optimal when they are applied to rare variants because of the rare variants’ low frequencies and weak signals. To alleviat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287894/ https://www.ncbi.nlm.nih.gov/pubmed/22373164 http://dx.doi.org/10.1186/1753-6561-5-S9-S56 |