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Identification of functional rare variants in genome-wide association studies using stability selection based on random collapsing

Genome-wide association studies are a powerful approach used to identify common variants for complex disease. However, the traditional genome-wide association methods may not be optimal when they are applied to rare variants because of the rare variants’ low frequencies and weak signals. To alleviat...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Fang, Yixin, Wang, Junhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287894/
https://www.ncbi.nlm.nih.gov/pubmed/22373164
http://dx.doi.org/10.1186/1753-6561-5-S9-S56