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Application of Bayesian regression with singular value decomposition method in association studies for sequence data
Genetic association studies usually involve a large number of single-nucleotide polymorphisms (SNPs) (k) and a relative small sample size (n), which produces the situation that k is much greater than n. Because conventional statistical approaches are unable to deal with multiple SNPs simultaneously...
Autores principales: | Kwon, Soonil, Yan, Xiaofei, Cui, Jinrui, Yao, Jie, Yang, Kai, Tsiang, Donald, Li, Xiaohui, Rotter, Jerome I, Guo, Xiuqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287895/ https://www.ncbi.nlm.nih.gov/pubmed/22373181 http://dx.doi.org/10.1186/1753-6561-5-S9-S57 |
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